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SMI-4a (TCS PIM-1 4a) is a potent inhibitor of Pim1 with IC50 of 17 nM modestly potent to Pim-2 does not significantly inhibit any other serine/threonine- or tyrosine-kinases
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Recombinant mouse myelin-associated glycoprotein (MAG/Siglec-4a) produced in HEK293 cells and supplied as a lyophilized, C-terminal 6xHis-tagged protein for biochemical and cell-based assays. Formulated from HEPES or phosphate buffer, the product has a reported molecular weight of 70-120 kDa and demonstrated activity in SH-SY5Y inhibition assays. Store frozen and aliquot to prevent repeated freeze-thaw.
Recombinant mouse MAG/Siglec-4a for functional assays.
Expressed in HEK293 to preserve mammalian post-translational modifications.
C-terminal 6xHis tag for purification and detection.
Lyophilized from buffered saline for stability and transport.
Reported molecular weight 70-120 kDa.
Demonstrated biological activity (ED50 ~3.13 μg/mL in SH-SY5Y assays).
Store at -20°C and aliquot to minimize freeze-thaw cycles.
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Dodeca-2E 4E 8Z 10Z/E-N-tetraenoic acid isobutylamide is a brain-penetrant substance and the main alkamide in Echinacea preparations which might be used for research of common cold and various upper respiratory infections[1]
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Nutlin-3a is a research-grade small-molecule MDM2 antagonist that stabilizes and activates p53, promoting apoptosis and autophagy in preclinical studies. Supplied as a purified solid for laboratory use, it is intended for cellular and biochemical investigation of p53-dependent pathways.
Potent MDM2 inhibitor that activates p53 signaling.
High purity suitable for research applications.
Characterized molecular weight and formula for analytical work.
Available in small quantities for experimental testing.
Documented in literature for studies of apoptosis and autophagy.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More